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Many people microdose with LSD by cutting up their tabs into tiny little pieces, and guessing the dosage by the size of the paper. However this isn’t ideal, for several reasons:

  • LSD is not always laid perfectly evenly. In the manufacturing process, sheets are soaked in a liquid LSD solution, then dried – but sometimes this drying does not occur perfectly evenly, leaving some sections of the paper slightly more concentrated than others. Because we are so sensitive to LSD, and we’re talking about such tiny amounts when it comes to microdosing, a single tab could have major variations in concentration from one millimeter to the next.
  • You’re probably not super-accurate with scissors. Unless you have a micro-cutting robot or something, it’s probably tough to accurately cut out that perfect, 8ug slice of tab that is your ideal microdose.
  • It takes ages and risks degrading your LSD. It’s tough to cut a tiny bit of paper into even tinier bits – and unless you’re wearing gloves, it’s possible that your sweaty grasp could start to degrade the tab during your cutting session.

Not the most accurate…

For these reasons, a more accurate (and easier) way of microdosing with LSD is volumetrically. It’s really simple. All you need is a small bottle, a 1ml syringe, and some distilled water or alcohol.

Fill up your small bottle with 10ml of distilled water or alcohol. Some people say that alcohol preserves the LSD better – other people say that distilled water is fine. We’ve even heard of some people using a 50/50 mix of alcohol and water. Whatever you do, don’t use tap water, as it will degrade your LSD.

When it comes to alcohol, the simpler the better. Vodka is great. If you can find pure ethanol, that’ll work perfectly, although you’ll probably want to dilute it a little.

To your 10ml of water/alcohol, add a single tab of LSD – which should be 100ug.

Shake the bottle around a bit, and leave it at room temperature or in the fridge for a day or two. If the bottle is clear, wrap some aluminum foil around it to prevent the LSD from being degraded by light.

After a couple of days, your LSD dissolve into the liquid (NOTE: The paper will still be there – however, the LSD that has been laid on the blotter paper will have dissolved into the distilled water).

Now, you just need to take 1ml with your syringe for a 10ug dose. If you microdose with less than 10ug, simply scale it to your volume – 0.6ml is 6ug, 0.8ml is 8ug, and so on.

You don’t want anyone drinking your ‘special’ vodka

Don’t forget to wrap in foil to protect from light!

The lazy version – if you don’t have a 1ml syringe, and don’t want to buy one, you can just scale up the volumes. Put your 100ug tab in 150ml of water/alcohol, then use a 15ml shot glass to take a 10ug dose.

Keep your bottle at room temperature or in the fridge. LSD doesn’t like rapid temperature changes, so whatever you do, don’t freeze it. Make sure the bottle is in the dark.

It should last at least a few months – and probably longer if you’ve used alcohol.

Happy microdosing!

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  1. How do you take the doses after diluting. Do you just drink it? Or do you hold it in your mouth like with a tab?

    • Hey John,

      Thought I would reply here as I thought drinking would have the same effect as holding the liquid under my tongue, but it doesn’t. There clearly is some benefit to allowing the liquid to remain under your tongue (30-45sec). I haven’t pinpointed whether this is due to what you I have had to eat, and how that affects the absorption, but it clearly hits harder.

        • It’s the goblet cells in the mucous membranes. There’s a higher concentration under the tongue than in the esophagus. Almost all of the acid will be absorbed into the bloodstream long before the paper or tincture hits the intestinal tract.

      • There is a direct path/shortcut from under your tongue to your heart/bloodstream. If you ingest, it has to pass through stomach/liver to get to bloodstream.

        This is the same concept as tincturing cannabis vs edibles. You’re better off letting the gummy dissolve under your tongue.

  2. How should we be sure that one tab has 100ug of LSD on it? Is it somewhat “standard” practice to make one tab have 100ug? Thanks

    • It depends on the source and quality of manufacture. This 1p LSD analogue is probably 100 ug because the quality of manufacture is high, if you purchase “real” LSD 25 from god knows where it can be different

  3. I’m wondering if your calculations are correct? If you have 100 ug of acid and would like to get 10 microdoses of 10 ug each drop, wouldn’t you use 1mg of water/alcohol to dilute the 100 ug in it?

  4. Or perhaps I misunderstood and you indicated 10 ml of water/alcohol because it’s easier to measure each dose? I guess if you dilute 100 ug into 1 ml it’s much harder to measure unless you’re counting drop by drop? Am I correct? Thanks

    • Marciello thats correct.
      If you dissolved 100ug into 1ml of water you would have to measure 1/10th of a millilitre to get a 10ug dose.
      So yes dissolving 100ug into 10ml of water and measuring 1ml for a 10ug dose is much easier 😊
      Cheers Jay

    • No, as the degradation isn‘t due to microorganisms, but rather the minerals present in tap water. Use distilled water.

  5. I have a 500ml bottle of pure distilled water, I also have 230ug tab I’m not good with maths can someone please help me

    • Given that your dose is 230 ug, if you wanna use the whole 500 ml bottle, then a 10 ug dose would be (500 x 10) / 230 = 21.79 ml… so around 22 ml would give you your microdose..

      But it would be easier to do it with 100 ml water. Easier to dose and easier to store. Put 100 ml of the distilled water, then a 10 ug dose would be (100 x 10) / 230 = 4.35 ml … so if you take a syringe and take about 4 ml, you have your dose.

  6. This was an interesting article. However, it contains one major error: it assumes that all tabs will be 100ug of LSD. There is simply no way to determine this unless you have it sent to a lab and tested or you know the chemist who produced it and s/he tells you directly. As far as I know, there is no standard measuring unit for LSD tabs.

    If you’re like me, you’re simply going to have to run trials . . . be safe, everyone!

  7. Does the actual volume of water or alcohol matter? For example: I have a 1 dram (3.36 mL) vial with a dropper that provides 20 drops. If I dissolve the whole 100 ug tab into the water, will it not dissolve fully due to saturation?

  8. Has anyone tried using spring water? I understand the issue with tap water is the chlorine so I am guessing bottled spring water might be ok.

  9. Hi, do you need to remove the cardboard from the bottle once the product has diffused into the water. I didn’t know if doing so would leave less in the bottle but if the cardboard remains soaked in the liquid, will that not lessen the quantity available to pour anyway? In that case, the divided by 10 equation wouldn’t be quite accurate. Or is that negligible and won’t make much of a difference?
    Also, at the risk of asking a really stupid question, does the product disperse completely evenly regardless of the amount of liquid? Does it settle in anyway and need shaking before each dose? Thanks for your help 🙂

    • I marked 10 lines on the jar. Left it in closet for 3 days. Drank the next line, skipped two days and repeated.
      After microdosing for two weeks, I can say that I don’t notice any effects besides when you take it initially… get some energy and you feel happy. Haven’t noticed any reduction in anxiety or depression yet. My creativity has yet to take off as well. I will continue it for months to come and see if that changes after doing it for a few month.
      Never tripped on acid before, just want reprogram my mind. Thanks for listening! Ohhh btw, I left tab in there the whole time. I just swirl the jar around, drink, seal up, and put back in dark closet. Use distilled water.

  10. Ok help please! New to this mircodosing and suck at math.
    I have dissolved 4 original orange tablets (cinnamon flav) 100 ug each in 40 ml of Alcohol.
    How much do I dose with???

    • Jill, then you have 400ug for 40ml, that’s 100ug for 10ml, so your dose is 1ml if you want 10ug.
      I prepare that amount and use a small syringe sans needle to get the 1ml dose.

    • Ok, Jill. You have dissolved 400ug total (100ug x 4) in 40ml. So if you wanna take 10ug of acid, you should take 1ml of solution.

      You can find your dose by a simple proportion (read “—” as “contain”):

      solution volume — amount of acid
      ? your solution dose — desired acid dose

      For example:
      40ml — 400ug
      ? ml — 10ug

      ? = (40ml x 10ug) / 400ug
      ? = 1ml

  11. Assuming you buy 4 blotters of 100ug each, what would be the best method of storing the 1p-lsd for storage and later usage? Dissolve 1 blotter and keep the other 3 in a dark and dry place or just dissolve all blotters and use that bottle for future microdosing? I’d like to know how long I’d be able to store it before any mold or degrading will take place.

  12. Hi there, very keen to learn more about this and try micro dosing.

    First question: Would micro pellets act the same way as strips?

    I am looking at purchasing 5x150ug (in form of micropellets)

    So for a 10ug micro dose My plan is to use 100ml of distilled water or vodka

    (100*10)/150 = 6.5 – 7ml of solution. every three days

    Taking a microdose on Day 1. Then do NOT take a microdose on Day 2 or Day 3.

    Then, take another microdose on Day 4. As explained.

    Few other questions:

    Is my math correct
    Is water or vodka better
    How shelf stable will be the other 4 pellets be – should they last a couple of months if I keep them in a mason jar or container, room temp, in the dark?

    Looking forward to start and also purchase the Microdosing Course once these questions are answered!


  13. Hello John,
    My dose is in a sugar cube!
    This will of course take up some volume in the liquid. Do I just work with the same 100ml (ish) ratio and hope for the best and will the sugar suggest i should stick to either water or alcohol.

  14. Is it ok to use 99% Isopropyl alcohol for volumetric work? I’m thinking it would have to be diluted with a bit of water or something before ingesting.

    • Please don’t use isopropyl alcohol! From Wikipedia: “Isopropyl alcohol and its metabolite, acetone, act as central nervous system (CNS) depressants, and around 15 g of isopropyl alcohol can have a toxic effect on a 70-kg human if left untreated. Poisoning can occur from ingestion, inhalation, or skin absorption.” 15 g of isopropyl alcohol is about 15 ml. So if you followed the 1 tab in 100 ml -> 10 ml microdose strategy, this would be very risky. Diluting 10 ml of isopropyl alcohol in water is not going to help, because you would still be ingesting 10 ml of isopropyl alcohol. Please just buy some vodka or Everclear. Or you can buy distilled water at a grocery store, Walgreens, CVS, etc. If you search online, you can buy distilled water from Target for $0.99.

    • Wow dude, don’t use isopropyl! You could die….
      How about you just use Vodka, a chemical you know is safe to take in small proportions!

      Wow I’m amazed by people experimenting with things in such a senseless way.

      All you have to do is dilute a 100ug tab in 100ml of vodka to get a 5-10ml dose for easy maths. 10ml would give you a 10ug dose.
      Why make it any harder?

      AKA rubbing alcohol. Not at all the same as drinking alcohol which is ethyl alcohol. Drinking isopropyl can cause all sorts of problems, including coma and death.
      Please tell me you know how to use an internet search engine and aren’t relying on these message boards for answers to things like this… Maybe you already drank the rubbing alcohol?

  15. Wow man, don’t use isopropyl, you could die… who knows!

    How about you just stick with the safe, easy to access chemicals like vodka and water.
    100ml of vodka for a 100ug tab… simple, cheap and easy.
    10ml would give you 10ug does.
    5ml would give you a 5ug dose.

    I’m amazed how people would go out of their way to make this harder or more dangerous!
    Just keep it simple!

  16. I measured it out so 10ml of vodka would equal a microdose. Could I mix this with juice in the morning when taking it? Does that have any sort of effect on the LSD like how tap water can affect a LSD tab? Will it make my microdose less potent?

  17. I have a 30 mil container, I assume 3-100ug tabs then?
    Dropper measures 1ml so a full dropper would be the same as the original post measurement?

  18. “It’s really simple. All you need is a small bottle, a 1ml syringe, and some distilled water or alcohol.” So you say. Is that why all the comments here are from folks who can’t figure out how to do it? It is “really simple”: for you. Like computers, not everyone has your experience. Much easier to cut up a hit of acid. Maybe some micro-doses will be smaller/larger than others when one does this. Anyone who has experience with LSD is not going to freak out from an eighth of a hit, even if they do trip a little bit. I don’t think folks who have no experience with LSD should start with micro-dosing.

  19. Hi!
    I started putting a 100ug 1P-LSD blotter into 100ml of distilled water. Taking 7ml/7ug of this liqiuid already has a recognizable effect on me. Meaning I become a bit more calm/ in deeper touch with myself, but also more anxious if in the wrong environment ( something I can more or less control or let go as an abstract emotion etc. etc.)
    My question would be, if this is already ‘all’ one is supposed to ‘feel’ during microdosing days. I did not dare to microdose during work/uni yet since I wanted some time to experience the effects in a safe environment.
    Somewhere on the internet i read, that you’re supposed to take at least 10ug, if it is 1P even up to 25ug. Is this true? Or is it just fine to do as little as possible until you feel ‘something’, as light as it may be?
    Thank you guys for the help!

  20. Hey, I was wondering if you were to buy the lsd off the streets, how’re you to know why ug the tabs are?. Want to make sure before I test it

  21. hi i was wondering if u could backward the process. meaning if i disolved 100ug in 10ml, is there any ways that i can put 100ug of lsd back into 1tab form? thank u

    • Hi buddamommy,

      Unfortunately, once it’s been dissolved there is no way that I know of to reduce it back to a concentrated form.

      Please let me know if you have any additional questions and I’ll do my best to help out!

      – Britt at The Third Wave

  22. Wondering if you can use a CBD tincture instead of water/alcohol to titrate the LSD? Contents of the tincture: CBD extract, MCT oil, lemon essential oil, ginger, turmeric herbs, and stevia.

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