Choosing the Right Microdose: Psilocybin, LSD, Huachuma & More
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Episode 359
Paul F. Austin
In this special solo episode, adapted from a recent live training, Paul F. Austin explores one of the most important and often overlooked realities of microdosing: different substances create different outcomes.
Drawing on more than a decade of experience in psychedelic education and coaching, Paul compares psilocybin, LSD, huachuma (San Pedro), ketamine, and iboga through the lens of client goals, nervous system regulation, emotional processing, cognitive performance, and contraindications.
Paul explains why generic microdosing protocols often fall short, how practitioners can better match substances to individual needs, and why context, preparation, and integration matter far more than any single medicine. He also shares why huachuma has become the foundation of the Psychedelic Coaching Institute’s microdosing methodology and offers guidance for practitioners looking to support clients with greater precision and care.
Podcast Highlights
- Why generic microdosing protocols can fall short
- How psilocybin supports emotional processing and inner work
- LSD's role in focus, creativity, and physiological performance
- Why huachuma may be especially useful for nervous system regulation
- Ketamine's role in SSRI tapering and clinical support
- Iboga's potential for neurodegenerative conditions and brain injury
- How to match substances to a client's goals and baseline state
- Why contraindications and clinical-grade intake matter
- How microdosing can support post-journey integration
- Why "more medicine" is not always the answer
Show Links
This episode is brought to you by The Practitioner Certification Program by Third Wave’s Psychedelic Coaching Institute. To learn more about our flagship 6-month training program for coaches who want to integrate psychedelic modalities into their practice, click here.
The Microdosing Practitioner Certification empowers you to launch a sustainable practice built on integrity, science, and results. Learn Paul F. Austin’s signature San Pedro Microdosing Protocol, master somatic coaching skills, and confidently guide clients toward lasting transformation. Click here to learn more and apply.
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