Choosing the Right Microdose: Psilocybin, LSD, Huachuma & More
LISTEN ON:
Episode 359
Paul F. Austin
In this special solo episode, adapted from a recent live training, Paul F. Austin explores one of the most important and often overlooked realities of microdosing: different substances create different outcomes.
Drawing on more than a decade of experience in psychedelic education and coaching, Paul compares psilocybin, LSD, huachuma (San Pedro), ketamine, and iboga through the lens of client goals, nervous system regulation, emotional processing, cognitive performance, and contraindications.
Paul explains why generic microdosing protocols often fall short, how practitioners can better match substances to individual needs, and why context, preparation, and integration matter far more than any single medicine. He also shares why huachuma has become the foundation of the Psychedelic Coaching Institute’s microdosing methodology and offers guidance for practitioners looking to support clients with greater precision and care.
Podcast Highlights
- Why generic microdosing protocols can fall short
- How psilocybin supports emotional processing and inner work
- LSD's role in focus, creativity, and physiological performance
- Why huachuma may be especially useful for nervous system regulation
- Ketamine's role in SSRI tapering and clinical support
- Iboga's potential for neurodegenerative conditions and brain injury
- How to match substances to a client's goals and baseline state
- Why contraindications and clinical-grade intake matter
- How microdosing can support post-journey integration
- Why "more medicine" is not always the answer
Show Links
This episode is brought to you by The Practitioner Certification Program by Third Wave’s Psychedelic Coaching Institute. To learn more about our flagship 6-month training program for coaches who want to integrate psychedelic modalities into their practice, click here.
We’re excited to feature Golden Rule — our trusted resource for premium microdosing products designed to support clarity, creativity, and emotional well-being. From Psilocybin blends to LSD microdosing options, each formula is crafted with care, backed by science, and trusted by the Third Wave community.
Safe, intentional, and transformative — Golden Rule helps you feel more focused, connected, and aligned in your everyday life.
Want to experience the difference? Try Paul’s favorite microdosing picks — hand-selected for performance, mood, and daily flow.
Get a lifetime discount of 10% with code THIRDWAVE at checkout.
Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can’t and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn’t responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.
