Episode 313B
Dave Rabin M.D., Ph.D.
Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety.
Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work.
If you’re a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights.
Dr. Dave Rabin is a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro. He specializes in treatment-resistant depression, PTSD, and anxiety through innovative approaches that blend psychedelics, ketamine, and wearable tech. He is also executive director of the nonprofit Board of Medicine, helping to set clinical safety guidelines for alternative medicines.
Podcast Highlights
- How SSRIs blunt emotional range and alter awareness
- The neuroscience of serotonin and psychedelic receptors
- Serious risks of serotonin syndrome when mixing with SSRIs
- Ketamine’s role in tapering and unlocking neuroplasticity
- Practical tools to regulate the nervous system during SSRI withdrawal
- Recommended psilocybin strains for sensitive or anxious clients
- How long-term SSRI use may (or may not) affect psychedelic response
- Safety-first protocols for psychedelic integration
- The future of microdosing as a sustainable antidepressant approach
Show Links
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