Unsticking the Brain: Psychedelics, Inflammation, & Mental Health

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Episode 294

Austin Perlmutter, M.D.

In this episode of The Psychedelic Podcast, Paul welcomes Dr. Austin Perlmutter, a board-certified internal medicine physician, New York Times bestselling author, and researcher. Dr. Perlmutter shares his perspective on how psychedelics can help "unstick" the brain from harmful patterns, explores the relationship between inflammation and mental health, and discusses his current research on ayahuasca's effects on epigenetics and the microbiome. From understanding the biological basis of our mental states to finding balance in a modern world that often works against our wellbeing, this conversation offers valuable insights on integrating psychedelics with healthy lifestyle practices for optimal brain function and mental health.

Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher and international educator. His mission is to help people improve their health by targeting the biological basis of "stuckness" in our brains and bodies. His writing, presentations, podcasts, and online educational programs have reached millions. Dr. Perlmutter has been featured on PBS, Rolling Stone, Newsweek, NPR and other media outlets. He is a co-producer of the Alzheimer's, the Science of Prevention series, and host of the Better Brain Blueprint series. Dr. Perlmutter currently serves as the managing director at Big Bold Health, a food-as-medicine company where he published a pioneering study on plant nutrients and human aging through epigenetics. He also consults with the Helfgott Research Institute, researching the effects of ayahuasca on epigenetics, metabolism, microbiome and immune function.

Podcast Highlights

  • The biology of mental health and decision-making
  • Inflammation's crucial role in brain function
  • How psychedelics create perspective shifts
  • Balancing psychedelic use with lifestyle practices
  • Breaking the cycle of chronic inflammation
  • Understanding the autonomic nervous system's response
  • The microbiome's connection to brain health
  • Research on ayahuasca's epigenetic effects
  • The importance of post-psychedelic environments
  • Moving beyond the "psychedelic as panacea" mindset

This episode is brought to you by The Practitioner Certification Program by Third Wave’s Psychedelic Coaching Institute. To learn more about our flagship 10-month training program for coaches who want to integrate psychedelic modalities into their practice, click here.

 

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